One fine October afternoon, in 1933, a group of students of the UP College of Medicine; all distinguished and the cream of their respective classes; organized and established the MU SIGMA PHI, the first fraternity in the University of the Philippines College of Medicine. Dr. Fernando Calderon, the first Filipino Dean of the UP College of Medicine and the first Filipino Director of the Philippine General Hospital, became the fraternity's first Faculty Adviser.

Documenting the inaugural year, the founding members had a fraternity photograph taken by a prominent studio of Pre-War Manila at the Nurses' Home of the Philippine General Hospital. 

• The Founding Fathers of the Mu Sigma Phi The Founding Fathers of the Mu Sigma Phi
• New members join Mu Sigma Phi in 1934 New members join Mu Sigma Phi in 1934
• MU in the Philippine Collegian November 1933 Issue MU in the Philippine Collegian November 1933 Issue
• The inaugural ball in January 1934 The inaugural ball in January 1934
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